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Filtered Search Results
Apexbio Technology LLC LDN-212854 1432597-26-6 10mM (in 1mL DMSO)
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LDN-212854 (CAS 1432597-26-6) is a highly selective inhibitor of the bone morphogenetic protein (BMP) signaling pathway targeting ALK2 with an IC50 of 1 2 nM In kinase assays LDN-212854 demonstrates potent inhibition of constitutively active ALK2 (caALK2 IC50 16 nM) and displays substantially reduced activity against caALK5 (IC50 2 M) indicative of its BMP pathway selectivity over TGF- signaling Compared to caALK1 and caALK3 its inhibitory activity against caALK2 is 6- and 10-fold greater respectively In BMP receptor-transfected C2C12 cell models LDN-212854 preferentially inhibits caALK2-mediated signaling In transgenic models of heterotopic ossification treatment with LDN-212854 reduces ectopic bone formation This compound is a valuable tool for dissecting BMP/ALK2-driven signaling in cellular and in vivo studies
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LaMarKa Chemical Company POTASSIUM IODATE 0.0025N CUBE
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POTASSIUM IODATE 0.0025N (WITH 2.5% KI)-CUBE 5 GALLON20 liter(5 gal)
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Aqua Solutions Potassium chloride 0.1 M | 7447-40-7 | MFCD00011360 | 1 L
Potassium chloride 0.1 M | Mol Wt: 74.55 | 7447-40-7 | MFCD00011360 | 1 L
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Medchemexpress LLC Eprenetapopt Solution | HY-19980 10MM1ML DMSO SOL
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Eprenetapopt Solution
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Chemworld 50/50 GLYCERIN/WATER SOLUTION
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50/50 Glycerin/Water Solution - 1 Gallon
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LaMarKa Chemical Company Chlorophenol Red 0.04% W/V (0.4 gpl)
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Chlorophenol Red .04% W/V (0.4 Gpl)-Bottle Bottle 8Oz Plastic
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LaMarKa Chemical Company Silver Nitrate 0.05N(in Nitric Acid 1:1), 1l
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Silver Nitrate 0.05N(in Nitric Acid 1:1), 1l Amber Safety
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Rieke Metals LLC 5-METHOXYCARBONYLPYRIDIN-100ML
NC3557681 5-METHOXYCARBONYLPYRIDIN-100ML
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Aqua Solutions Potassium Hydrogen Phthalate 0.0100 Normal, NIST (1L)
Potassium Hydrogen Phthalate 0.0100 Normal, NIST (1L)
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Medchemexpress LLC ICL-CCIC-0019 100mg | 936498-64-5 | 572.46 | C26H44Br2N4 | 100 MG
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ICL-CCIC-0019 is a small-molecule inhibitor of choline kinase α (CHKα) that induces G1 cell-cycle arrest, endoplasmic reticulum stress, and apoptosis in cancer cell lines. It is supplied as a solid for research use and is available in multiple milligram pack sizes.
- Inhibits choline kinase α (CHKα) and alters cellular metabolism.
- Induces G1 cell-cycle arrest, endoplasmic reticulum stress, and apoptosis in cancer cell lines.
- High reported purity suitable for biochemical and cellular assays.
- Molecular weight 572.46 and molecular formula C26H44Br2N4.
- Available in small milligram-scale quantities for research applications.
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LAB ALLEY Hydrogen Peroxide 6% Solution, (Stabilized), Lab Grade 1 Liter.Recommended For Educational Or Research Laboratories.
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Hydrogen Peroxide 6% Solution, (Stabilized), Lab Grade 1 Liter.Recommended For Educational Or Research Laboratories. Hydrogen Peroxide 6% (Stabilized) is composed of 6% hydrogen peroxide (H2O2) and 94% water (H2O) with trace amount of acetic acid. Lab Grade Hydrogen Peroxide 6% is a clear, colorless liquid that contains stabilizers. Laboratory Grade Hydrogen Peroxide 6% contains intermediate purity and is suitable for educational or research laboratories; it is not safe to use in foods, drugs, or medicines. CAS Number 7722-84-1
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LaMarKa Chemical Company Hydrochloric Acid 0.08N THAM Endpoint, 4l
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Hydrochloric Acid 0.08N THAM Endpoint, 4l Plastic Jug
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Meridian Life Science MANGO MIX 250 REACTION
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MangoMix is a complete ready-to-go 2x reaction mix of the MangoTaq DNA Polymerase for carrying out primer extensions, requiring the user only to add water, template and primers.
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Medchemexpress LLC Lyn peptide inhibitor | 222018-18-0 | 99.35% | 2370.88 | 25 MG
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Lyn peptide inhibitor is a potent and cell-permeable inhibitor of the Lyn-coupled IL-5 receptor signaling pathway, designed to keep other signals intact. It works by blocking Lyn activation and inhibiting the binding of Lyn tyrosine kinase to the βc subunit of IL-3/GM-CSF/IL-5 receptors. This inhibitor is suitable for studying asthma, allergic, and other eosinophilic disorders.
- Potent and cell-permeable inhibitor
- Blocks Lyn activation
- Inhibits binding of Lyn tyrosine kinase to the βc subunit of IL-3/GM-CSF/IL-5 receptors
- Can be used for the study of asthma, allergic, and other eosinophilic disorders
- Targets IL-5 and IL-3
- Inhibits Src and Interleukin related pathways
- Involved in Protein Tyrosine Kinase/RTK and Immunology/Inflammation pathways
- Sequence: {Stearoyl}-Tyr-Gly-Tyr-Arg-Leu-Arg-Arg-Lys-Trp-Glu-Glu-Lys-Ile-Pro-Asn-Pro-NH2
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Medchemexpress LLC Cathepsin K inhibitor 6 | 325775-42-6 | 98.2% | 251.30 | 25 MG
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Cathepsin K inhibitor 6 is an inhibitor of cathepsin K (Cat K) with an IC50 of 17 nM. It also exhibits inhibitory effects on cathepsin L (IC50: 0.05 μM) and cathepsin B (IC50: 0.3 μM).
- Solid appearance
- White to off-white color
- Inhibits cathepsin K with an IC50 of 17 nM
- Inhibits cathepsin L with an IC50 of 0.05 μM
- Inhibits cathepsin B with an IC50 of 0.3 μM
- Powder storage: -20°C for 3 years; 4°C for 2 years
- In solvent storage: -80°C for 6 months; -20°C for 1 month
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